SV40-derived vectors provide effective transgene expression and inhibition of HIV-1 using constitutive, conditional,and pol III promoters
- 1 July 2001
- journal article
- Published by Springer Nature in Gene Therapy
- Vol. 8 (13) , 1033-1042
- https://doi.org/10.1038/sj.gt.3301481
Abstract
At the forefront of medicine, Gene Therapy brings you the latest research into genetic and cell-based technologies to treat disease. It also publishes Progress & Prospects reviews and News and Commentary articles, which highlight the cutting edge of the field.Keywords
This publication has 23 references indexed in Scilit:
- Inhibition of HIV-1 by an anti-integrase single-chain variable fragment (SFv): delivery by SV40 provides durable protection against HIV-1 and does not require selectionGene Therapy, 1999
- HIV-1 Regulatory/Accessory Genes: Keys to Unraveling Viral and Host Cell BiologyScience, 1998
- Use of SV40-based vectors to transduce foreign genes to normal human peripheral blood mononuclear cellsGene Therapy, 1997
- Expression of small, therapeutic RNAs in human cell nucleiGene Therapy, 1997
- Inhibition of human immunodeficiency virus type 1 replication by regulated expression of a polymeric Tat activation response RNA decoy as a strategy for gene therapy in AIDS.Proceedings of the National Academy of Sciences, 1993
- The transcriptional start site for a human U6 small nuclear RNA gene is dictated by a compound promoter element consisting of the PSE and the TATA boxNucleic Acids Research, 1992
- The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation.Proceedings of the National Academy of Sciences, 1991
- Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replicationCell, 1990
- Extensive variation of human immunodeficiency virus type-1 in vivoNature, 1988
- Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used.Genes & Development, 1988