The microsomal demethylation of N,N-dimethylbenzamides: Substituent and kinetic deuterium isotope effects

This publication has 15 references indexed in Scilit:

• Acyloxymethyl as a drug protecting group. Kinetics and mechanism of the hydrolysis of N-acyloxymethylbenzamides
  Journal of the Chemical Society, Perkin Transactions 2, 1991
• Mechanism of the microsomal demethylation of 1-aryl-3,3-dimethyltriazenes
  Biochemical Pharmacology, 1990
• Oxidation of the methyl groups of N,N-dimethylbenzamides by a cytochrome P450 mono-oxygenase model system
  Tetrahedron Letters, 1990
• Differences between rodents and humans in the metabolic toxification of N,N-dimethylformamide
  Toxicology and Applied Pharmacology, 1989
• Identification by proton NMR of N-(hydroxymethyl)-N-methylformamide as the major urinary metabolite of N, N-dimethylformamide in mice
  Life Sciences, 1986
• Review of the biodistribution and toxicity of the insect repellentN,N‐diethyl‐m‐toluamide (DEET)
  Journal of Toxicology and Environmental Health, 1986
• ¹H and ¹³C NMR spectra of the rotational isomers of N‐hydroxymethylamides and derivatives
  Magnetic Resonance in Chemistry, 1985
• The formation and metabolism of N-hydroxymethyl compounds—III
  Biochemical Pharmacology, 1983
• Chemicals, cancer, and cytochrome P-450
  Journal of Chemical Education, 1982
• Isotope effects in O- and N-demethylations mediated by rat liver microsomes: An application of direct insertion electron impact mass spectrometry
  Chemico-Biological Interactions, 1974