Mucociliary clearance from bullfrog (Rana cantesbiana) lung.

Publisher Website
Google Scholar
Abstract
The lungs of large bullfrogs (Rana cantesbiana) were evaginated through the glottis and partially inflated to study mucociliary clearance from the lung. The method is described in detail. Direct observations and still and cinephotographic records were made for 6-8 hr. At 22 C and relative humidity of 100% ciliary transport of mucus marked with material such as India ink averaged 2.2 cm/min. on the major longitudinal ridge. Mucus was cleared approximately half as fast on each generation of annular and smaller ridges. Crypt clearance depended upon moisture, mucus retraction, and ciliated tufts which made mucus move in one direction. This effect was enhanced by inflation and deflation of the lung. Lung movement, moisture, and heating increased mucociliary clearance rate. Drying, cooling, particle overload, and mechanical damage to the surface cells decreased or stopped it.

This publication has 3 references indexed in Scilit: