Oxygen Uptake by Treponema pallidum
Open Access
- 1 July 1974
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 10 (1) , 123-127
- https://doi.org/10.1128/iai.10.1.123-127.1974
Abstract
Virulent Treponema pallidum has been shown to consume O 2 at a rate similar to that of the known aerobic spirochaete, Leptospira. Such O 2 uptake is cyanide sensitive, indicating a functioning cytochrome oxidase. Inhibition of O 2 uptake by azide, chlorpromazine, and amytal further suggests a functioning electron transport system for the oxidation of nicotinamide adenine dinucleotide (reduced) to O 2 . Evidence is consistent with the probability that this terminal electron-transport system is coupled to oxidative phosphorylation. The potential significance of these findings is discussed.Keywords
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