GASTRIC ACIDITY IN THYROID DYSFUNCTION
- 30 December 1933
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 101 (27) , 2097-2099
- https://doi.org/10.1001/jama.1933.02740520007002
Abstract
It has been recognized for some time that hyperthyroidism causes changes in gastric acidity and that in some cases there is an absence of hydrochloric acid. Hardt1in 1916 called attention to the fact that thyroid feeding caused lowered gastric acidity in normal dogs. Barker2in 1918 mentioned hypochlorhydria, and King3in 1919 noted that achlorhydria and achylia occur in hyperthyroidism. Lockwood4in 1925 and Moll and Scott5in 1927 reported a high incidence of achlorhydria in exophthalmic goiter. Following this line of thought, Truesdell6in 1926 showed that a lowering of acidity could be produced regularly by feeding thyroid to dogs, and in some achlorhydria was produced. On the other hand, Crile7and his co-workers have held that the same mechanism that produced hyperthyroidism could in some cases produce peptic ulcer. He has also stated that denervation of the suprarenals and aKeywords
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