THE RESPIRATORY EXCHANGE IN FROGS DURING MUSCULAR EXERCISE AND AFTER INJECTION OF INSULIN

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Abstract
In winter frogs at room temperature insulin depresses the general metabolic rate as measured by the gaseous exchange, but causes a rise in R.Q. from 0.7 to 1, indicating a change in combustion from fat to carbohydrate. If convulsions occur the R.Q. rises above 1, then falls later to 0.4 or 0.5, and finally rises to the normal 0.7. A similar change in R.Q. follows muscular exercise in normal frogs; but in insulin frogs the caloric output is a fraction of the normal, whereas in exercised normal frogs it is several times the normal. The frog as well as man incurs an O2 debt during severe muscular exercise.

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