Faculty Opinions recommendation of Effect of expedited treatment of sex partners on recurrent or persistent gonorrhea or chlamydial infection.

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Abstract
Unfortunately, rates of successful treatment of sex partners of persons with Chlamydia trachomatis remain low, and resources to detail public health staff to assist in partner notification efforts are not available in the US. In the absence of such efforts, patients are often asked to notify their partners of the need for medical evaluation and treatment but this approach has been deemed a public health failure. In this randomized controlled trial, 2751 patients (23 percent male) with diagnosed gonococcal infection, chlamydial infection, or both were assigned either to an "expedited treatment group" or a standard referral group. Patients in the expedited treatment group were given "partner packets" of cefixime and/or azithromycin to distribute to their partners, without requiring a formal medical evaluation of the partners. In the standard referral arm, patients simply notified their sex partners of the need for evaluation and treatment. Patients assigned to expedited treatment of sexual partners were significantly more likely to report that all of their partners had been treated compared with those assigned to the standard referral arm (61 versus 49 percent). The trial also demonstrated a significant benefit in lowering the number of recurrent infections among those assigned to expedited treatment (relative risk of reinfection 0.75, 95% confidence interval [CI] 0.56 to 0.97). This Recommendation is of an article referenced in an F1000Prime Report also written by Jeanne Marrazzo and Robert Suchland.

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