Arsenamide in the Treatment of Infections with the Periodic Form of the Filaria, Wuchereria Bancrofti

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Abstract
We have already reported (Thetford et al., 1948) the apparently successful treatment with arsenamide 1 of six adult negro males infected with the periodic form of Wuchereria bancrofti in St. Croix, the Virgin Islands. This paper summarizes similar treatment of twelve additional cases in the same area. These subjects were, as the previous six, all adult male Negroes who had lived all or most of their lives on St. Croix. They were selected because microfilariae had been found in their night blood. Of the twelve, eight were asymptomatic and four (J. G., J. J., R. D., and E. B.) had right scrotal hydroceles but were otherwise asymptomatic. The microfilariae were counted in thick smears made from 0.1 cc. of venous blood drawn between 10 and 12 o'clock at night. Such counts were made before treatment, immediately after the completion of treatment, and periodically thereafter as the patients were available up to a year after treatment.

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