The Modulation of Transthyretin Tetramer Stability by Cysteine 10 Adducts and the Drug Diflunisal: DIRECT ANALYSIS BY FLUORESCENCE-DETECTED ANALYTICAL ULTRACENTRIFUGATION
Open Access
- 2 May 2008
- journal article
- Published by Elsevier
- Vol. 283 (18) , 11887-11896
- https://doi.org/10.1074/jbc.m709638200
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- Expression, purification, and in vitro cysteine-10 modification of native sequence recombinant human transthyretinProtein Expression and Purification, 2007
- Diflunisal Analogues Stabilize the Native State of Transthyretin. Potent Inhibition of AmyloidogenesisJournal of Medicinal Chemistry, 2003
- Tabulation of human transthyretin (TTR) variants, 2003Amyloid, 2003
- Tetramer Dissociation and Monomer Partial Unfolding Precedes Protofibril Formation in Amyloidogenic Transthyretin VariantsJournal of Biological Chemistry, 2001
- Reduction of the amyloidogenicity of a protein by specific binding of ligands to the native conformationProtein Science, 2001
- Review: TTR Amyloidosis—Structural Features Leading to Protein Aggregation and Their Implications on Therapeutic StrategiesJournal of Structural Biology, 2000
- Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation ModelingBiophysical Journal, 2000
- Direct Observation of the Self-Association of Dilute Proteins in the Presence of Inert Macromolecules at High Concentration via Tracer Sedimentation Equilibrium: Theory, Experiment, and Biological SignificanceBiochemistry, 1999
- Clinical Significance of Histopathologic Patterns of Cardiac AmyloidosisMayo Clinic Proceedings, 1984
- A boundary anomaly found in the ultracentrifugal sedimentation of mixturesTransactions of the Faraday Society, 1946