ACUTE NONSPECIFIC PERICARDITIS WITH CARDIAC TAMPONADE: A FATAL CASE ASSOCIATED WITH ANTICOAGULANT THERAPY

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Abstract
A 76 year-old Negro female received dicumarol in therapeutic doses for a suspected myocardial infarction. The patient expired suddenly on the 14th hospital day with cardiac tamponade. Another such case was reported by McCord and Taguchi in 1951. Because of the great dissimilarity in the immediate and ultimate prognosis, and in the light of present day anticoagulant therapy for myocardial infarction, the importance of clinical differentiation is fundamentally important. Hemorrhage occurs in these patients at a time when the epicardial and pericardial surfaces are covered by young proliferating capillaries and fibroblastic tissue. Anticoagulant therapy is contraindicated in patients with acute nonspecific pericarditis.

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