Comparison of the efficacy of nicardipine and nifedipine in patients with chronic stable angina

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Abstract
1 This parallel, randomised single-blind study examined the anti-anginal efficacy of 90 mg/day nicardipine compared with that of 60 mg/day nifedipine in 40 patients with chronic stable angina pectoris. 2 Treadmill exercise test results showed both drugs to be effective in improving exercise time. Both the number of anginal attacks per week and glyceryl trinitrate consumption were reduced. No significant difference was shown between nicardipine and nifedipine in the efficacy parameters. 3 Nicardipine was associated with fewer side-effects and in fewer patients than nifedipine.