GROWTH HORMONE AND RADIO-SULFATE INCORPORATION IN COSTAL CARTILAGE
- 1 June 1961
- journal article
- research article
- Published by Bioscientifica in Acta Endocrinologica
- Vol. 37 (2) , 176-182
- https://doi.org/10.1530/acta.0.0370176
Abstract
The characteristics and nature of the effect of growth hormone on the incorporation of radio-sulfate into the costal cartilage of hypophysectomized rats has been studied. The time-response studies indicate that a reliable estimation of growth hormone activity can be ascertained within a 24 hour period, and a reproducible dose-related response can be obtained at dosage levels ranging from 12-48 [mu]g. Growth hormone stimulates the synthesis of organic sulfates and accumulation of inorganic sulfates within 48 hours.Keywords
This publication has 6 references indexed in Scilit:
- THE EFFECT OF PROLACTIN ON S35FIXATION IN THE COSTAL CARTILAGE OF THE HYPOPHYSECTOMIZED RATEndocrinology, 1959
- The response of costal cartilage to changes in hormonal environmentCellular and Molecular Life Sciences, 1959
- Influence of Hypophysectomy and Growth Hormone on Cartilage Sulfate Metabolism.Experimental Biology and Medicine, 1953
- ISOLATION OF CHONDROITIN SULFATES-S35 FROM ARTICULAR CARTILAGE OF RATSJournal of Biological Chemistry, 1951
- Effect of Cortisone upon Chondroitin Sulfate Synthesis by Animal Tissues.Experimental Biology and Medicine, 1951
- ON THE POSSIBLE UTILIZATION OF SULFATE SULFUR BY THE SUCKLING RAT FOR THE SYNTHESIS OF CHONDROITIN SULFATE AS INDICATED BY THE USE OF RADIOACTIVE SULFURJournal of Biological Chemistry, 1949