Data are presented and analyzed on the demographic variables (location, age, sex, and race) of people perishing in fires in the state of Maryland in 1972/1973, on the physical causes of these fires, and on the most likely medical effects. Carbon monoxide as asphyxiant, cigarettes as ignition source, and the disproportionately large involvement of children and the elderly are pointed up. The contributory effects of alcohol ingestion, particularly in men in the 40 to 60 years age group, are described.