BOWEN'S DISEASE OF THE CORNEA
- 1 April 1944
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 31 (4) , 310-315
- https://doi.org/10.1001/archopht.1944.00890040048007
Abstract
In 1912 Bowen1 first described in detail a disease of the skin which he called precancerous dermatosis. It is characterized by the presence of lenticular or nummular spots which coalesce to form asymmetric plaques of various sizes. These plaques may be squamous or scabby, papular or wrinkled. Sometimes they regress and assume the appearance of atrophic spots. They may be a shade darker than the skin or may vary from pale pink to dark pink or copper red. Their outline is sharp; there is no halo of congestion. When the scab is removed, a wet, pink surface appears, which may be smooth, granular or, more rarely, warty. But soon new layers cover the area. The disease is extremely chronic and slowly progressive. Cases in which the disease developed over twenty, thirty or even forty years have been recorded. Histologically, the lesion has the appearance of an epithelioma composed ofKeywords
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