Integration of IS3 into IS2 generates a short sequence duplication
- 1 December 1979
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 177 (1) , 85-89
- https://doi.org/10.1007/bf00267256
Abstract
The Gal+ allele IS2-43 is known to segregate Gal- clones. Among 11 Gal- segregants, one was shown to be due to the integration of IS3 into IS2-43. Precise excision of the integrated IS3 element occured at a rate of 5x10-9/cell/generation. DNA sequence analysis revealed that the termini of the IS3 element have the relation of imperfect inverted repeats and it is now flanked by a 3bp or 4bp duplication, a size which has not been seen before with other elements.This publication has 31 references indexed in Scilit:
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