Synthesis and anti-Influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives
- 3 June 2002
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 12 (15) , 1929-1932
- https://doi.org/10.1016/s0960-894x(02)00330-x
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Syntheses of C-3-Modified Sialylglycosides as Selective Inhibitors of Influenza Hemagglutinin and NeuraminidaseEuropean Journal of Organic Chemistry, 2000
- Synthesis of a polymeric 4- N -linked sialoside which inhibits influenza virus hemagglutininBioorganic & Medicinal Chemistry Letters, 2000
- Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and InhibitorsAngewandte Chemie International Edition in English, 1998
- A Lysoganglioside/Poly-L-glutamic Acid Conjugate as a Picomolar Inhibitor of Influenza HemagglutininAngewandte Chemie International Edition in English, 1998
- Polyacrylamides Bearing Pendant α-Sialoside Groups Strongly Inhibit Agglutination of Erythrocytes by Influenza Virus: The Strong Inhibition Reflects Enhanced Binding through Cooperative Polyvalent InteractionsJournal of the American Chemical Society, 1996
- Effective Inhibitors of Hemagglutination by Influenza Virus Synthesized from Polymers Having Active Ester Groups. Insight into Mechanism of InhibitionJournal of Medicinal Chemistry, 1995
- Polyacrylamides Bearing Pendant .alpha.-Sialoside Groups Strongly Inhibit Agglutination of Erythrocytes by Influenza A Virus: Multivalency and Steric Stabilization of Particulate Biological SystemsJournal of Medicinal Chemistry, 1994
- Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variationNature, 1981
- Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolutionNature, 1981
- Inhibition of Influenza Virus Replication in Tissue Culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): Mechanism of ActionJournal of General Virology, 1976