Astemizole in the Treatment of Hay Fever
- 1 May 1983
- Vol. 38 (4) , 227-231
- https://doi.org/10.1111/j.1398-9995.1983.tb01615.x
Abstract
A double‐blind parallel trial of astemizole, pheniramine and placebo was carried out in 15 patients with hay fever. Astemizole is a new potent H1‐antihistamine with long duration of action but devoid of central activity. Evaluation criteria were daily symptom‐ and side effect score cards, daily nasal peak flow measurements, clinical examination and blood tests. Control of nasal symptoms was significantly better with both antihistamines than with placebo. Tiredness and anticholinergic side effects were less common in the astemizole group than in the pheniramine group. No significant changes in the “safety evaluation” blood tests were observed.Keywords
This publication has 1 reference indexed in Scilit:
- Relationship between nasal and conjunctival tests in patients with allergic rhinitisClinical and Experimental Allergy, 1978