On the Effects of Tannic Acid on Erythrocyte Membrane Acetylcholinesterase

1 April 1968

journal article
research article
Published by Frontiers Media SA in Experimental Biology and Medicine

Vol. 127 (4) , 1240-1245
https://doi.org/10.3181/00379727-127-32919

Abstract

Treatment of human erythrocytes with tannic acid caused irreversible inactivation of the surface located acetylcholinesterase (ACHE). This effect was dependent on concentration, time, temperature, and pH. The ACHE inactivation was prevented by albumin but not by coating the cells with blood-group specific antibodies. The enzyme was not affected by the other phenolic compounds tested.

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