The IL-2/IL-15 Receptor Systems: Targets for Immunotherapy
- 1 January 2002
- journal article
- review article
- Published by Springer Nature in Journal of Clinical Immunology
- Vol. 22 (2) , 51-56
- https://doi.org/10.1023/a:1014416616687
Abstract
Although interleukin-2 (IL-2) and -15 (IL-15) share two receptor subunits and many functions, at times they provide contrasting contributions to T-cell-mediated immune responses. IL-2, through its...Keywords
This publication has 50 references indexed in Scilit:
- Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: A phase I/II clinical trialProceedings of the National Academy of Sciences, 1999
- Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts.1998
- Soluble IL-15 Receptor α-Chain Administration Prevents Murine Collagen-Induced Arthritis: A Role for IL-15 in Development of Antigen-Induced ImmunopathologyThe Journal of Immunology, 1998
- The Transcription Factor Interferon Regulatory Factor 1 (IRF-1) Is Important during the Maturation of Natural Killer 1.1+ T Cell Receptor–α/β+ (NK1+ T) Cells, Natural Killer Cells, and Intestinal Intraepithelial T CellsThe Journal of Experimental Medicine, 1998
- Requirement for IRF-1 in the microenvironment supporting development of natural killer cellsNature, 1998
- Radioimmunotherapy of interleukin-2R alpha-expressing adult T-cell leukemia with Yttrium-90-labeled anti-Tac.1995
- The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.Proceedings of the National Academy of Sciences, 1994
- A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.Proceedings of the National Academy of Sciences, 1994
- Development and proliferation of lymphocytes in mice deficient for both interleukins‐2 and ‐4European Journal of Immunology, 1994
- Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-7 ReceptorScience, 1993