ANTIBODY TO RO IN A POPULATION OF PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS - DISTRIBUTION, CLINICAL AND SEROLOGICAL ASSOCIATIONS

  • 1 January 1983
    • journal article
    • research article
    • Vol. 10  (3) , 380-386
Abstract
Anti-Ro occurs in 1/3 of systemic lupus erythematosus (SLE) patients with equal prevalence at all ages, ages at onset of SLE, and disease durations. In SLE anti-Ro is associated with xerophthalmia but not rheumatoid factor (RF). Anti ds-DNA [double stranded DNA] rather than anti-Ro or RF is associated with SLE arthritis. A positive correlation was found between increased anti ds-DNA levels and the prevalence of anti-Ro in SLE patients'' sera. Anti-Ro may have considerable value as a diagnostic marker for SLE.