Survival of Adrenalectomized Rats With and Without Replacement Therapy Following X-Irradiation
Open Access
- 31 October 1951
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 167 (2) , 345-348
- https://doi.org/10.1152/ajplegacy.1951.167.2.345
Abstract
Whole-body X-irradiation decreased the survival time of adrenalectomized rats. Treatment with desoxycorticosterone acetate or whole gland adrenal extract increased the survival of irradiated adrenalectomized rats. The length of survival after discontinuance of therapy of irradiated adrenalectomized rats treated with DCA or adrenal extract was similar to that of the unirradiated, untreated adrenalectomized rat.Keywords
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