THE RATE OF ENTRANCE OF RADIO SODIUM INTO THE AQUEOUS HUMOR AND CEREBROSPINAL FLUID

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Abstract
The rate of movement of Rd Na24 into the aqueous humor and cerebrospinal fluid has been measured. In the anesthetized dog the Rd Na24 conc. in the aqueous reaches about 75% of the plasma level 45 mins. after its intraven. inj.; this represents a much more rapid rate of turnover than has been indicated previously by transport studies involving conc. differences between plasma and aqueous. The rate of entrance was found to be somewhat slower in unanesthetized animals. In anesthetized animals the rate of approach to equilibrium between plasma and the cerebrospinal fluid sampled from the cisterna magna is 25-40% as great as in the case of the aqueous humor.