HPLC determination of tocopherol, retinol, dehydroretinol and retinyl palmitate in tissues of lake char (Salvelinus namaycush) exposed to coplanar 3,3′,4,4′,5‐pentachlorobiphenyl
- 1 March 1994
- journal article
- research article
- Published by Oxford University Press (OUP) in Environmental Toxicology and Chemistry
- Vol. 13 (3) , 473-476
- https://doi.org/10.1002/etc.5620130315
Abstract
Tocopherol, retinol, dehydroretinol, and retinyl palmitate were measured by reversed‐phase HPLC in liver, kidney, and plasma of lake char exposed to orally administered coplanar 3,3′,4,4′,5‐pentachlorobiphenyl (PCB). Tocopherol concentrations were unaffected after eight weeks. Liver retinol, dehydroretinol, and retinyl palmitate concentrations were lower, whereas kidney retinyl palmitate was elevated in PCB‐exposed groups. Tissue retinoid concentrations provide sensitive indicators of coplanar PCB exposure in fish.Keywords
This publication has 24 references indexed in Scilit:
- What Have Biomarkers Told Us About the Effects of Contaminants on the Health of Fish-eating Birds in the Great Lakes? The Theory and a Literature ReviewJournal of Great Lakes Research, 1993
- Retinoids: From metabolism to environmental monitoringChemosphere, 1992
- Polychlorinated and polybrominated biphenyl congeners and retinoid levels in rat tissues: Structure-activity relationshipsToxicology and Applied Pharmacology, 1992
- Coplanar PCBs in fish and mussels from marine and estuarine waters of New York StateEcotoxicology and Environmental Safety, 1992
- Simultaneous determination of retinol, α-tocopherol and β-carotene in serum by isocratic high-performance liquid chromatographyJournal of Chromatography B: Biomedical Sciences and Applications, 1991
- Protective role of vitamin E in biological systemsThe American Journal of Clinical Nutrition, 1991
- Yolk retinoids (vitamin a) in eggs of the herring gull and correlations with polychlorinated dibenzo‐p‐dioxins and dibenzofuransEnvironmental Toxicology and Chemistry, 1990
- Vitamin E: Antioxidant Activity, Biokinetics, and BioavailabilityAnnual Review of Nutrition, 1990
- Assessment of relative toxicity of chlorinated dibenzo- -dioxins, dibenzofurans, and biphenyls in Lake Ontario salmonids to mammalian systems using toxic equivalent factors (TEP)Chemosphere, 1989
- Bioconversion pathway of astaxanthin into retinol2 in mature rainbow trout (Salmo Gairdneri Rich.)Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1989