Electromyography of the Urinary Bladder

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Abstract
Electromyograms obtained from the isolated urinary bladders of various mammalian types are indistinguishable in form from records secured in situ from normal human subjects. The frequency of activity as well as the magnitude of bio-electric potentials observed in excised bladder preparations were increased by giving parasympathomimetic drugs and by adrenergic blockade. The reverse was found to be true for sympathomimetic substances and parasympathetic blockade. Records secured from strips of human bladder musculature were identical in contour to those obtained from isolated whole bladders, or from the human bladder in situ. Maximum activity was shown by tissue samples from the more central portions of the bladder and electropotential activity was minimal in tissue strips from the dome and from the vesical neck. These findings indicate that the electrocystomyogram secured by way of transurethral electrodes placed within the human bladder represents vesical activity in response to parasympathetic bombardment.