Cortisone-induced Transformation of Ovaries into Testes in Larval Frogs.
- 1 December 1950
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 75 (3) , 715-718
- https://doi.org/10.3181/00379727-75-18317
Abstract
Summary Cortisone, like 3 other tested alkyl substituted androstanes, causes the transformation of ovaries of frog larvae into testes. Its action is initially anti-ovariogenic, and sex reversal follows by a compensatory development of the meduallary rudiment. The dosages that produce sex reversal are high in comparison with the threshold values of testosterone and methyltestosterone.Keywords
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