Quantitative Short-term Study of Anal Sphincter Function After Chemoradiation for Rectal Cancer
Open Access
- 1 February 2001
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 136 (2) , 192-196
- https://doi.org/10.1001/archsurg.136.2.192
Abstract
IN APRIL 1990, a panel of experts under the auspices of the National Cancer Institute recommended adjuvant therapy consisting of radiotherapy, chemotherapy, or both for all patients with stages II and III rectal cancer.1 During the last 2 decades, the technical feasibility of proctectomy with coloanal anastomosis (PCAA) has increased with the advent of circular stapling devices and the knowledge that distal margins of resection of 2 cm are adequate.2,3 Thus, it is expected that an increasing number of patients with rectal cancer will receive a combination of sphincter-preserving surgery and pelvic radiation. However, few data are currently available to quantitatively assess the effects of irradiation on anorectal function.Keywords
This publication has 1 reference indexed in Scilit:
- Improved Survival with Preoperative Radiotherapy in Resectable Rectal CancerNew England Journal of Medicine, 1997