The discovery and validation of new drug targets in cancer

This publication has 37 references indexed in Scilit:

• A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
  The EMBO Journal, 1998
• Antiangiogenic tumour therapy: will it work?
  Trends in Pharmacological Sciences, 1998
• Mutations of mitotic checkpoint genes in human cancers
  Nature, 1998
• Cell Division Gatekeepers Identified
  Science, 1998
• Malignant Transformation of Mammalian Cells Initiated by Constitutive Expression of thePolo-like Kinase1
  Biochemical and Biophysical Research Communications, 1997
• Kinetochore Localization of Murine Bub1 Is Required for Normal Mitotic Timing and Checkpoint Response to Spindle Damage
  Cell, 1997
• Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes.
  The Journal of cell biology, 1996
• Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from Xenopus Egg Extracts
  Science, 1996
• Angiogenesis in cancer, vascular, rheumatoid and other disease
  Nature Medicine, 1995
• The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.
  Molecular and Cellular Biology, 1994