PUBERTAL DEVELOPMENT IN GIRLS WITH SEXUAL PRECOCITY AFTER DISCONTINUATION OF TREATMENT WITH CYPROTERONE-ACETATE

  • 1 January 1980
    • journal article
    • research article
    • Vol. 35  (2) , 149-154
Abstract
Girls with sexual precocity (n = 24) who were treated with cyproterone acetate were followed for periods from 1-8 1/2 yr after the discontinuation of therapy. Their further pubertal development and the resumption or appearance of menstruation followed a natural course within the wide limits of physiological variability. Puberty apparently resumes its natural course following cessation of treatment with cyproterone acetate; the reproductive ability of these patients apparently will not be affected.

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