One‐Step Synthesis of 2‐Amino‐3‐cyano‐4‐ aryl‐1,4,5,6‐tetrahydropyrano[3,2‐c]quinolin‐5‐one Derivatives Using KF–Al2O3 as Catalyst
- 1 January 2004
- journal article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 34 (16) , 3021-3027
- https://doi.org/10.1081/scc-200026662
Abstract
A series of 2‐amino‐3‐cyano‐4‐aryl‐1,4,5,6‐tetrahydropyrano[3,2‐c] quinolin‐5‐one derivatives were synthesized by the reaction of arylaldehyde, malononitrile, and 4‐hydroxyquinolin‐2‐one in ethyl alcohol at 80°C catalyzed by KF–Al2O3. The structure of the product was confirmed by x‐ray analysis.Keywords
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