Synthesis of Ac-Asp-Gly-Ser and Ac-Asp-Pro-Leu-Gly-NH2
- 12 January 2009
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 23 (6) , 642-649
- https://doi.org/10.1111/j.1399-3011.1984.tb03137.x
Abstract
The syntheses of Ac-Asp-Gly-Ser and Ac-Asp-Pro-Leu-Gly-NH2 are described. The 2 peptides were prepared in solution by stepwise elongation using the DCC [N,N''-dicyclohexylcarbodiimide] method with additives (HOSu[N-hydroxysuccinamide] or HOBt[1-hydroxybenzotriazole]). The push-pull method was also used in the synthesis of Ac-Asp-Gly-Ser. A racemization test of the amino acids in this peptide was performed. [These are the structures postulated for 2 CNS peptides.].This publication has 34 references indexed in Scilit:
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