Long-Term Follow-Up of Children with Surgically Treated Yesicorenal Reflux: Postoperative Incidence of Urinary Tract Infections, Renal Scars and Arterial Hypertension

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Abstract
With a mean follow-up of 10.8 years, 160 female and 29 male patients were investigated after successful correction of vesicoureterorenal reflux. All patients suffered from urinary tract infection (UTI) preoperatively, while postoperatively 42% of the patients developed further UTIs but with a significantly diminished rate of febrile infections. In comparison to a group of patients without postoperative UTI (n = 16), the uroepithelial cells of those patients with a high infection rate after reflux correction showed a significantly lower bacterial growth suppression (n= 37). Renal scars were found in 22% of the investigated renal units with operated ureters (n = 211). Of the preoperatively unscarred kidneys, 3.4% developed new scars during the observation period, mainly within the first 2 years after the operation. In 7 (11.5%) of the 61 patients with renal scars, moderate arterial hypertension was found.

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