31P NMR studies of adenosine‐stimulated ATP synthesis in perfused luteinized ovaries

Abstract
31P NMR spectroscopy was utilized to study phosphate metabolism of perfused ovaries. In luteinized ovaries, a loss in ATP of ∼ 30% with a concomitant acidification was reversed by 50 μM adenosine. The results suggest that in the ovaries, adenosine can serve to regulate ATP concentration during periodic hypoxic challenges. © 1986 Academic Press, Inc.