Variation in the Ascorbic Acid Requirements for Saturation of Nine Normal Young Women

Abstract
A simplified modification of the method using responses to the test dose for the determination of saturation needs of ascorbic acid was used. Daily urinalysis for ascorbic acid were omitted and only the 24-hour samples of urine before and after the test dose were analyzed. A more liberal intake of ad libitum foods was allowed and the subjects as far as possible lived and ate under their normal dormitory conditions. Of 9 young women, 6 were found to have an ascorbic acid requirement for saturation above 1.4 mg. per kg., but not greater than 1.8 mg. One subject had a requirement of 0.6 mg. or less per kilogram, while 2 had requirements of 2.2 mg. or above per kilogram.