Induction and Characterization of Suppressor T Cells and Soluble Factors with Modified Timothy Grass Pollen AgB
- 1 January 1981
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 65 (2) , 129-137
- https://doi.org/10.1159/000232748
Abstract
Previous studies demonstrated that antigen B (AgB), a major antigen of timothy grass pollen, modified by photooxidation (Ox-AgB) does not react with rabbit, human, or mouse antibodies directed against AgB and does not induce antibodies reactive with either native or modified AgB. However, immunization of mice with Ox-AgB in alum induces significant T helper cell activity. In this review, we describe the conditions and kinetics for Ox-AgB induction of T suppressor cells, the secretion of AgB-specific T suppressor factor (TSF), and the partial purification of AgB-specific TSF.This publication has 0 references indexed in Scilit: