CEREBRAL METABOLISM AND ELECTRICAL ACTIVITY DURING INSULIN HYPOGLYCEMIA IN MAN

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Abstract
Simultaneous observations were made of the electroencephalographic changes and oxygen utilization of the brain and of blood sugar levels of patients with schizophrenia receiving the insulin treatment. The O uptake was a better indicator of cerebral metabolism than was the blood sugar. A direct relationship was disclosed between the frequency of the a waves and the cerebral O consumption, both declining during hypoglycemia and increasing after the adm. of carbohydrate. The [delta] index displayed an inverse relationship for it was augmented during the period of diminished O utilization of the brain.

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