Synthesis of a Tricyclic Mescaline Analogue by Catalytic C−H Bond Activation
- 22 March 2003
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 5 (8) , 1301-1303
- https://doi.org/10.1021/ol034228d
Abstract
[reaction: see text] A tetrahydrobis(benzofuran) mescaline analogue has been prepared in six steps and 38% overall yield from (4'-O-methyl)methyl gallate. The key step in this synthesis is a tandem cyclization reaction via directed C[bond]H activation followed by olefin insertion.Keywords
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