A UV-Sensitive Mutant of Arabidopsis Defective in the Repair of Pyrimidine-Pyrimidinone(6-4) Dimers
- 17 September 1993
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 261 (5128) , 1571-1574
- https://doi.org/10.1126/science.8372351
Abstract
Plants are continually subjected to ultraviolet-B (UV-B) irradiation (290 to 320 nanometers) as a component of sunlight, which induces a variety of types of damage to the plant DNA. Repair of the two major DNA photoproducts was analyzed in wild-type Arabidopsis thaliana and in a mutant derivative whose growth was sensitive to UV-B radiation. In wild-type seedlings, repair of cyclobutane pyrimidine dimers occurred more slowly in the dark than in the light; repair of this photoproduct was not affected in the mutant. Repair, in the dark, of pyrimidine-pyrimidinone(6-4) dimers was defective in the UV-sensitive mutant.Keywords
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