Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network
Open Access
- 1 March 2009
- journal article
- research article
- Published by American Diabetes Association in Diabetes
- Vol. 58 (3) , 609-619
- https://doi.org/10.2337/db08-1180
Abstract
OBJECTIVE—Wnt signaling inhibits adipogenesis, but its regulation, physiological relevance, and molecular effectors are poorly understood. Here, we identify the Wnt modulator Dapper1/Frodo1 (Dact1) as a new preadipocyte gene involved in the regulation of murine and human adipogenesis.Keywords
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