Response of Infant and Adult Mice to Lymphocytic Choriomeningitis Virus Infection

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Abstract
Freshly isolated strains of lymphocytic choriomeningitis virus induced inapparent infection and immunity in infant mice. A mouse-adapted strain, however, caused obvious signs of infection and a high mortality rate among infant mice. Adult mice were fully susceptible to both freshly isolated and mouse-adapted virus. These findings are in keeping with the epizoology of the disease in naturally infected mouse colonies.
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