Effect of klebsiella capsular antisera on lymphocytes from patients with ankylosing spondylitis
- 1 November 1981
- journal article
- research article
- Published by Microbiology Society in Journal of Medical Microbiology
- Vol. 14 (4) , 451-456
- https://doi.org/10.1099/00222615-14-4-451
Abstract
The cytotoxicity of Klebsiella capsular antisera for lymphocytes from 10 HLA B27-positive patients with ankylosing spondylitis and 8 B27-negative normal control subjects was examined. None of the antisera was cytotoxic for lymphocytes from 9 patients but several antisera were cytotoxic for the lymphocytes from 1 patient. There were no differences between the results obtained with lymphocytes from the 9 patients and those with lymphocytes from the normal controls. If Klebsiella carriage is important in the pathogenesis of ankylosing spondylitis, the results of this investigation suggest that the capsular antigen is probably not involved.This publication has 5 references indexed in Scilit:
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- Faecal carriage of klebsiella by patients with ankylosing spondylitis and rheumatoid arthritis.Annals of the Rheumatic Diseases, 1980
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- Sequential studies in ankylosing spondylitis. Association of Klebsiella pneumoniae with active disease.Annals of the Rheumatic Diseases, 1978
- ARTHRITIS DUE TO SALMONELLA TYPHIMURIUM - REPORT OF 12 CASES OF MIGRATORY ARTHRITIS IN ASSOCIATION WITH SALMONELLA TYPHIMURIUM INFECTION1964