Developmental biology of a neural cell adhesion molecule
- 1 August 1984
- journal article
- Published by Springer Nature in Nature
- Vol. 310 (5978) , 549-554
- https://doi.org/10.1038/310549a0
Abstract
A membrane glycoprotein isolated from embryonic brain has been shown to be a ligand in the formation of cell-cell bonds. The molecule, called neural cell adhesion molecule (N-CAM), participates in several aspects of neural development, including the formation of plexiform layers, neurite fasciculation and nerve-muscle interactions. Experiments in vivo indicate that N-CAM-mediated adhesion is essential to the orderly assembly of the visual system.Keywords
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