Reversing the Discovery Paradigm: A New Approach to the Combinatorial Discovery of Fluorescent Chemosensors
- 30 June 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (29) , 10124-10125
- https://doi.org/10.1021/ja043682p
Abstract
We report here a new approach to the discovery of fluorescent chemosensors in which a new signaling mechanism allows a core fluorophore to be used in a combinatorial search for new binding events, thus reversing the reigning discovery paradigm.Keywords
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