Asymmetry of DNA replication fork progression in Werner's syndrome
Open Access
- 15 September 2002
- journal article
- research article
- Published by Wiley in Aging Cell
- Vol. 1 (1) , 30-39
- https://doi.org/10.1046/j.1474-9728.2002.00002.x
Abstract
Human aging is associated with accumulation of cells that have undergone replicative senescence. The rare premature aging Werner's syndrome (WS) provides a phenocopy of normal human aging and WS pati...Keywords
This publication has 52 references indexed in Scilit:
- A Minimal Exonuclease Domain of WRN Forms a Hexamer on DNA and Possesses both 3‘−5‘ Exonuclease and 5‘-Protruding Strand Endonuclease ActivitiesBiochemistry, 2002
- Interactions between the Werner Syndrome Helicase and DNA Polymerase δ Specifically Facilitate Copying of Tetraplex and Hairpin Structures of the d(CGG) Trinucleotide Repeat SequenceJournal of Biological Chemistry, 2001
- The Werner syndrome protein: an updateBioEssays, 2000
- Defending genome integrity during DNA replication: a proposed role for RecQ family helicasesBioEssays, 1999
- Werner Syndrome ProteinJournal of Biological Chemistry, 1998
- Genetics and the pathobiology of ageingPhilosophical Transactions Of The Royal Society B-Biological Sciences, 1997
- Effects of topoisomerase II inhibition in lymphoblasts from patients with progeroid and “chromosome instability” syndromesCancer Genetics and Cytogenetics, 1996
- FFA-1, a Protein That Promotes the Formation of Replication Centers Within NucleiScience, 1995
- Decrease in the average size of replicons in a Werner syndrome cell line by Simian Virus 40 infectionExperimental Cell Research, 1983
- Prolongation of S phase and whole cell cycle in Werner's syndrome fibroblastsExperimental Gerontology, 1982