Myocardial Ischemia
- 5 May 1977
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 296 (18) , 1034-1041
- https://doi.org/10.1056/nejm197705052961804
Abstract
Biochemical TechnicsIt has been known for over 20 years that irreversibly injured myocardial cells release enzymes. In the hours after an acute myocardial infarction, the plasma concentrations of these enzymes gradually rise, reach a peak and then fall progressively. The laboratory measurement of serum enzymes is a standard practice in the diagnosis of acute myocardial infarction. Lactic dehydrogenase (LDH) is elevated in the several days after an acute myocardial infarction; this enzyme can be separated into five distinct components or isoenzymes, according to their speed of migration in an electrophoretic field. The myocardium contains predominantly LDH5, although . . .This publication has 105 references indexed in Scilit:
- Favorable Effects of Hyaluronidase on Electrocardiographic Evidence of Necrosis in Patients with Acute Myocardial InfarctionNew England Journal of Medicine, 1977
- Comparison between the effects of nitroprusside and nitroglycerin on ischemic injury during acute myocardial infarction.Circulation, 1976
- The protective effect of hyperosmotic mannitol in myocardial ischemia and necrosis.Circulation, 1976
- An improved basis for enzymatic estimation of infarct size.Circulation, 1975
- Effects of glucose, insulin and potassium infusion on tissue metabolic changes within first hour of myocardial infarction in the baboon.Circulation, 1975
- Estimation of Infarct Size in Man and its Relation to PrognosisCirculation, 1972
- Reduction by Hyaluronidase of Myocardial Necrosis following Coronary Artery OcclusionCirculation, 1972
- Coronary Artery Occlusion in the Conscious DogCirculation, 1972
- Effect of Glucose-Insulin-Potassium Infusion on Myocardial Infarction following Experimental Coronary Artery OcclusionCirculation, 1972
- Effects of Intraaortic Balloon Counterpulsation on the Severity of Myocardial Ischemic Injury following Acute Coronary OcclusionCirculation, 1972