Activity of Pyridyl and Phenyl Ether Analogues of Juvenile Hormone Against Coleoptera and Lepidoptera in Stored Grain1

Abstract
Five pyridyl or phenyl ether analogues of juvenile hormone were each mixed separately with whole wheat or ground wheat medium and tested for activity against stored grain insects. The chemical (E)-5{5-(3,3-dimethyl-2-oxiranyl)-3-methyl-2-pentenyl}oxy-2-ethylpyridine was effective at 100 ppm in preventing larval development from eggs of Tribolium confusum Jacquelin duVal, T. castaneum (Herbst), and Sitophilus oryzae (L.). The compound also suppressed adult progeny of Rhyzopertha dominica (F.), Oryzaephilus surinamensis (L.), Plodia interpunctella (Hubner), Cadra cautella (Walker), and Sitotroga cerealella (Olivier) at doses of 10–250 ppm. Other compounds, (E)-5-{3,7-dimethyl-2,6-octadienyl)oxy}-2-ethylpyridine, (E)-5-{(3,7-dimethyl-2,6-octadienyl)oxy}-2-methylpyridine, and 3-{5-(4-ethylphenoxy)-3-methyl-3-pentenyl}-2,2-dimethyloxirane, were less effective except in the case of T. confusum where a mixture of 2-ethyl-3-{3-ethyl-5-(4-ethylphenoxy)-pentyl}-2-methyloxirane and 2-ethyl-3-{5-(4-ethylphenoxy)-2,3-dimethyl-pentyl}-2-methyloxirane at 1 ppm was efficacious against adult progeny.

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