Solitary plasmacytoma of bone and soft tissues.

Publisher Website
Google Scholar
Abstract
Between 1956-1978, 9 patients with solitary plasmacytoma of bone (SPB) and 7 with extramedullary plasmacytoma (EMP) were treated at the University of Washington Hospital and Swedish Tumor Institute [Seattle, Washington, USA]. All but 1 patient had local radiotherapy. In the SPB group, 6 of 9 patients progressed to multiple myeloma (MM) and 5 died of disease within 3 yr after dissemination. Three of the 9 patients are alive at 5, 8 and 16 yr, respectively. In the EMP group, none of the7 patients progressed to MM. Five are alive 16 mo. to 23 yr after radiotherapy. Since there are no reliable criteria for prospectively distinguishing true solitary plasmacytoma from occult MM, all patients with apparently isolated plasmacytoma should receive local radiotherapy with curative intent.