PLASMA KININ AND KININOGEN LEVELS IN THE FEMALE RAT DURING THE OESTROUS CYCLE, PREGNANCY, PARTURITION AND THE PUERPERIUM
Open Access
- 1 February 1974
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 50 (2) , 237-241
- https://doi.org/10.1111/j.1476-5381.1974.tb08567.x
Abstract
1 Plasma kininogen concentration of the female rat did not change during the oestrous cycle but increased two-fold during gestation. Plasma kininogen did not change during parturition, rose in the first puerperal day and then rapidly declined to non-pregnant levels. 2 Free kinin levels in the blood of non-pregnant female rats were low and inconstant. Free kinin was undetectable in the blood of pregnant rats, but was found in four out of ten parturient rats. 3 After administration of the kininase inhibitor dimercaprol (30 mg/kg i.p.), free kinin was present in the blood of six parturient rats. Dimercaprol caused appearance of free kinin in the blood of only one out of six non-pregnant rats. 4 It appears that the plasma kinin system is activated to a small degree during parturition.Keywords
This publication has 14 references indexed in Scilit:
- THE EFFECT OF THE OESTROUS CYCLE, PREGNANCY AND REPRODUCTIVE HORMONES ON THE KININASE ACTIVITY OF RAT BLOODReproduction, 1972
- PLASMA KININ AND KININOGEN LEVELS IN WOMEN DURING PREGNANCY AND IN LABOURReproduction, 1972
- SECRETION RATES OF OESTROGENS INTO THE OVARIAN VENOUS BLOOD OF PREGNANT RATSReproduction, 1972
- Estrogen Secretion by the Rat Ovaryin VivoDuring the Estrous Cycle and PregnancyEndocrinology, 1969
- Der Kininogenspiegel von Ratten und Kaninchen während der GestationCellular and Molecular Life Sciences, 1968
- Determination of plasma kinin and kininogen levels in manThe Journal of Physiology, 1967
- Bradykininogen in the Blood of Women during Pregnancy, Labor, and PuerperiumPublished by Springer Nature ,1966
- A MICROMETHOD FOR DETERMINATION OF BRADYKININOGEN UNDER SEVERAL CONDITIONS*Annals of the New York Academy of Sciences, 1963
- THE BRADYKININOGEN CONTENT OF PLASMA FROM WOMEN IN LABOUR*BJOG: An International Journal of Obstetrics and Gynaecology, 1962
- OXYTOCIC ACTIVITY OF BLOOD IN PARTURIENT AND LACTATING WOMENJournal of Clinical Endocrinology & Metabolism, 1961