HYPERBILIRUBINAEMIA AND IDIOPATHIC HYPOPITUITARISM IN THE NEWBORN PERIOD

Abstract
Two infants with idiopathic panhypopituitarism presented with severe neonatal hypoglycemia, hepatomegaly and hyperbilirubinemia (direct and indirect). Abnormal liver function tests returned to normal over a 5-8 mo. period. The growth rate in the absence of detectable growth hormone [GH] was 50% of normal during the first 6 mo. The effect of GH on somatomedian levels and growth rate during the 1st year of life in 1 infant is described.