Basal Copper Excretion in Wilson's Disease

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Abstract
The basal copper excretion of six cases of Wilson''s disease has been estimated before and after treatment with penicillamine. In all cases a striking fall was demonstrated after several months. These results suggest that this test may be a relatively simple method of assessing the extent to which the body has been depleted of copper and may thus be a useful guide to the choice of long-term maintenance dosage of penicillamine.