SOLUBILIZATION OF PARTICULATE PROTEINS AND NONELECTROLYTES BY CHAOTROPIC AGENTS
- 1 April 1969
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 62 (4) , 1129-1136
- https://doi.org/10.1073/pnas.62.4.1129
Abstract
Chaotropic ions (those ions which favor the transfer of apolar groups to water) provide a highly effective means for the resolution of membranes and multicomponent enzymes and for increasing the water solubility of particular proteins and nonelectrolytes. The action of chaotropic agents is related to their effect on the structure and lipophilicity of water.Keywords
This publication has 14 references indexed in Scilit:
- The denaturing effectiveness of guanidinium, carbamoylguanidinium, and guanylguanidinium saltsBiochemistry, 1968
- Stability of an amide-hydrogen bond in an apolar environmentBiochemistry, 1968
- Influence of Denaturing Agents on Solvent Structure*Biochemistry, 1967
- Depolymerization of F-Actin by Concentrated Solutions of Salts and Denaturing Agents1Journal of the American Chemical Society, 1965
- The Effect of Concentrated Salt Solutions on the Activity Coefficient of Acetyltetraglycine Ethyl EsterJournal of the American Chemical Society, 1965
- Neutral Salts: The Generality of Their Effects on the Stability of Macromolecular ConformationsScience, 1964
- A rapid method for the preparation of highly purified cytochrome oxidaseBiochimica et Biophysica Acta, 1962
- The effect of various monovalent anions on myosin B solutions the identification of actin as a product of ATP actionBiochimica et Biophysica Acta, 1960
- Some Factors in the Interpretation of Protein DenaturationAdvances in Protein Chemistry, 1959